Publications

SELECTED PUBLICATIONS

1. Sirsi SR, Flexman ML, Vlachos F, Huang J, Hernandez SL, Kim HK, Johung TB, Gander JW, Reichstein AR, Lampl BS, Wang A, Hielscher AH, Kandel JJ, Yamashiro DJ, Borden MA. “Contrast ultrasound imaging for identification of early responder tumor models to anti-angiogenic therapy.” Ultrasound Med Biol. 2012 Jun, 38(6): 1019-29. PMID: 22425376

2. Flexman ML, Vlachos F, Kim HK, Sirsi SR, Huang J, Hernandez SL, Johung TB, Gander JW, Reichstein AR, Lampl BS, Wang A, Borden MA, Yamashiro DJ, Kandel JJ, Hielscher AH. “Monitoring early tumor response to drug therapy with diffuse optical tomography.” J Biomed Opt. 2012 Jan;17(1):016014. PMID: 22352664

3. Anastassiou D, Rumjantseva V, Cheng W, Huang J, Canoll PD, Yamashiro DJ, Kandel JJ. “Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo.” BMC Cancer. 2011 Dec 30;11(1):529. PMID: 22208948

4. Zeng S, Zhang QY, Huang J, Vedantham S, Rosario R, Ananthakrishnan R, Yan SF, Ramasamy R, Dematteo RP, Emond JC, Friedman RA, Schmidt AM. “Opposing roles of RAGE and Myd88 signaling in extensive liver resection.” FASEB J. 2012 Feb; 26(2)882-93. PMID: 22075646

5. Fisher JC, Gander JW, Haley MJ, Hernandez SL, Huang J, Chang YJ, Johung TB, Guarnieri P, O’Toole K, Yamashiro DJ, Kandel JJ. “Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor.” Vasc Cell. 2011 Oct 6;3:22. PMID: 21978392

6. Lipskar AM, Glick RD, Huang J, Fisher JC, DeVoti J, Pica R, Edelman M, Sterinberg BM, Soffer SZ. “Cyclooxygenase 2 mediates the antiangiogenic effect of rapamycin in Ewing sarcoma”. J Pediatr Surg. 2009; 44(6): 1139-46. PMID: 19524730

7. Zaghloul N, Hernandez SL, Bae JO, Huang J, Fisher JC, Lee A, Kadenhe-Chiweshe A, Kandel JJ, Yamashiro DJ. “Vascular endothelial growth factor blockade rapidly elicits alternative proangiogenic pathways in neuroblastoma.” Int J Oncol. 2009; 34(2): 401-7.

PMID: 19148474

8. Huang J, Bae JO, Tsai JP, Kadenhe-Chiweshe A, Papa J, Lee A, Zeng S, Kornfeld ZN, Ullner P, Zaghloul N, Ioffe E, Nandor S, Burova E, Holash J, Thurston G, Rudge J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. “Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade.” Int J Oncol. 2009; 34(1):79-87. PMID: 19082480

9. Funahashi Y, Hernandez SL, Das I, Ahn A, Huang J, Vorontchikhina M, Sharma A, Kanamaru E, Borisenko V, Desilva DM, Suzuki A, Wang X, Shawber CJ, Kandel JJ, Yamashiro DJ, Kitajewski J. “A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis.” Cancer Res. 2008; 68(12): 4727-35. PMID: 18559519

10.  Kadenhe-Chiweshe A, Papa J, McCrudden KW, Frischer J, Bae JO, Huang J, Fisher J, Lefkowitch JH, Feirt N, Rudge J, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ. “Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation”. Mol Cancer Res. 2008; 6(1): 1-9. PMID: 18234958

11. Masciotti J, Abdoulaev G, Provenzano F, Hur J, Papa J, Bae J, Huang J, Yamashiro D, Kandel J, Hielscher A. “Optical Tomographic and Magnetic Resonance Imaging of Tumor Growth and Regression in Mice treated with VEGF Blockade”. Conf Proc IEEE Eng Med Biol Soc. 2005;1: 205-8. PMID: 17282148

12. Lee A, Frischer JS, Serur A, Huang J, Bae JO, Kornfield ZN, Eljuga L, Shawber CJ, Feirt N, Mansukhani M, Stempak D, Baruchel S, Bender JG, Kandel JJ, Yamashiro DJ. “Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling”. Cancer Res. 2006; 66(8): 4378-84. PMID: 16618763

13.  Frischer JS, Huang J, Serur A, Kadenhe-Chiwishe A, McCrudden KW, O’Toole K, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. “Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature”. Int J Oncol. 2004, 25(3): 549-53. PMID: 15289855

14. Huang J, Frischer J, New T, Kim E, Serur A, Lee A, Kadenhe-Chiwishe A, Pollyea D, Yokoi A, Holash J, Yancopoulos G, Kandel J, Yamashiro D.  “TNP-470 promotes initial vascular sprouting in xenografts tumors”. Mol Cancer Ther. 2004; 3(3): 335-43. PMID: 15026554

15.  Frischer JS, Huang J, Serur A, Kadenhe A, Yamashiro DJ, Kandel JJ. “Biomolecular markers and  involution of hemangiomas”. J Pediatr Surg. 2004; 39(3): 400-4. PMID: 15017560

16. Huang J, Soffer S, Kim E, McCrudden K, Huang Joe, New T, Manley C, Middlesworth W, O’Toole K, Kadenhe-Chiwishe A, Yamashiro D, Kandel J.  “Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis”. Mol Cancer Res. 2004; 2(1):36-42. PMID: 14757844

17. Yokoi A, McCrudden K, Huang J, Kim E, Soffer SZ, Frischer J, Serur A, New T, Yuan J, Mansukhani M, O’Toole K, Yamashiro D, Kandel J. “Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms’ tumor”. J Pediatr Surg. 2003; 38(11): 1569-73. PMID: 14614702

18.  Kaicker S, McCrudden K, Beck L, New T, Huang J, Frischer J, Serur A, Kadenhe-Chiwishe A, Yokoi A, Kandel J, Yamashiro D. “Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma”. Int J Oncol. 2003; 23(6):1651-5. PMID: 14612937

19. Yokoi A, McCrudden K, Huang J, Kim E, Soffer SZ, Frischer J, Serur A, New T, Yuan J, Mansukhani M, O’Toole K, Yamashiro D, Kandel J. “Blockade of her2/neu decreases VEGF expression but does not alter HIF-1 distribution in experimental Wilms tumor”. Oncol Rep. 2003; 10(5):1271-4. PMID: 12883692

20. Huang J, Frischer J, Serur A, Kadenhe A, Yokoi A, McCrudden K, New T, O’Toole K, Zabski S, Rudge J, Holash J, Yancopoulos G, Yamashiro DJ, Kandel JJ. “Regression of established tumors and metastases by potent vascular endothelial growth factor blockade”. Proc Natl Acad Sci USA. 2003; 100 (13): 7785-90. PMID: 12805568

21. McCrudden K, Hopkins B, Frischer J, Novikov A, Huang J, Kadenhe A, New T, Yokoi A, Yamashiro D, Kandel J, Middlesworth W. “Anti-VEGF antibody in experimental hepatoblastoma: suppression of tumor growth and altered angiogenesis”. J Pediatr Surg. 2003; 38(3):308-14. PMID: 12632340

22. Kim E, Serur A, Huang J, Manley C, McCrudden K, Soffer S, Ring L, New T, Zabski S, Rudge J, Holash J, Yancopoulos G, Kandel J, Yamashiro D. “Anti-VEGF agents cause persistent vascular co-option in xenograft model of neuroblastoma”.  Proc Natl Acad Sci USA. 2002;99(17):11399-404. PMID: 12177446

23. McCrudden K, Yokoi A, Thosani A, Soffer S, Kim E, Huang J, Manley C, O’Toole K, Yamashiro D, Kandel J, Middlesworth W. “Topotecan is anti-angiogenic in experimental hepatoblastoma”. J Pediatr Surg. 2002;37(6):857-61. PMID: 12037749

24. Soffer S, Kim E, Huang J, McCrudden K, Yokoi A, Moore J, Manley C, O’Toole K, Middlesworth W, Stolar C, Yamashiro D, Kandel J.  “Resistance of a VEGF-producing tumor to anti-VEGF antibody: unimpeded growth of human rhabdoid tumor xenografts”. J Pediatr Surg. 2002;37(3):528-31. PMID: 11877682

25. Huang J, Soffer S, Kim E, Yokoi A, Moore J, McCrudden K, Manley C, Middlesworth W, O’Toole K, Stolar C, Yamashiro D, Kandel J. “P53 accumulation in favorable-histology Wilms tumor is associated with angiogenesis and clinically aggressive disease”. J Pediatr Surg. 2002; 37(3):523-27. PMID: 11877681

26. Kim E, Soffer S, Huang J, McCrudden K, Yokoi A, Manley C, Middlesworth W, Kandel J, Yamashiro D. “Distinct response of experimental neuroblastoma to combination anti-angiogenic strategies”. J Pediatr Surg. 2002; .37(3): 518-22. PMID: 11877680

27. Soffer S, Moore J, Kim E, Huang J, Manley C, O’Toole K, Stolar C, Yamashiro D, Kandel J. “Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor”. J Pediatr Surg. 2001; 36(12):1781-84. PMID: 11733904

28. Soffer S, Moore J, Kim E, Huang J, Manley C, O’Toole K, Stolar C, Yamashiro D, Kandel J. “Combination anti-angiogenic therapy: increased efficacy in a murine model of Wilms tumor”. J Pediatr Surg. 2001;36(8):1177-81. PMID: 11479851

29. Kim E, Moore J, Huang J, Soffer S, Manley CA, O’Toole K, Middlesworth W, Stolar CJ, Kandel JJ, Yamashiro DJ. “All angiogenesis is not the same: Distinct patterns of response to antiangiogenic therapy in experimental neuroblastoma and Wilms tumor”. J Pediatr Surg. 2001;36(2):287-90. PMID: 11172417

30. Huang J, Moore J, Soffer S, Kim E, Rowe D, Manley CA, O’Toole K, Middlesworth W, Stolar C, Yamashiro D, Kandel J. “Highly specific antiangiogenic therapy is effective in suppressing growth of experimental Wilms tumors”. J Pediatr Surg. 2001;36(2):357-61. PMID: 11172434

31. Rowe DH, Huang J, Li J, Manley C, O’Toole KM, Stolar CJH, Yamashiro DJ, Kandel JJ. “Suppression of primary tumor growth in a mouse model of human neuroblastoma”. J Pediatr Surg. 2000; 35(6): 977-81. PMID: 10873048

32. Abou-Mohamed GA, Huang J, Oldham CD, Taylor TA, Jin L, Caldwell RB, May SW, Caldwell RW. “Vascular and endothelial actions of inhibitors of substance P amidation”. J Cardio Pharma.2000; 35(6): 871-80. PMID: 10836720

33. Rowe DH, Huang J, Kayton ML, Thompson R, Troxel A, O’Toole KM, Yamashiro D, Stolar CJ, Kandel J. “Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms’ tumor”.  J Pediatr Surg. 2000; 35(1): 30-33. PMID: 10646769

34. Kaesemeyer WH, Caldwell RB, Huang J, Caldwell RW. “Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions”. J Am Coll Cardiol. 1999; 33(1): 234-41. PMID: 9935036

35. Desai HK, Hart BP, Caldwell RW, Huang J, Pelletier SW. “Certain Norditterpenoid alkaloids and their cardiovascular action”. J Nat Prod. 1998; 61(6): 743-48. PMID: 9644057

36. Oldham CD, Li CZ, Feng J, Scott RO, Wang WZ, Moore AB, Girard PR, Huang J, Caldwell RB, Caldwell RW, May SW. “Amidative peptide processing and vascular function”. Am J Physiol. 1997; 273(42): C1908-14. PMID: 9435496

37. Jiang JP, Gu XL, Ma G, Yi J, Huang J, Xu X. “Local injection of Bleomycin A5 for Lymphangioma in children: analysis of 100 cases”. Chung Hua Wai Ko Tsa Chil. 1989; 27(12):741-42. PMID: 2483986